304am永利集团(中国)有限公司-Official Website

Name: Qiao Lu

Office Location: 280 South Chongqing Road, Room 1108, West #5 Building, Shanghai, China 200025

Lab Location: 280 South Chongqing Road, Room 610, West #5 Building, Shanghai, China 200025

E-mail: qiao.lu@sjtu.edu.cn

Education and Career

2024-present Investigator, Shanghai Jiaotong University, Shanghai Institute of Immunology

2019-2024 Postdoctoral Fellow, New York University, New York, NY, USA

2018-2019 Postdoctoral Associate, Yale University, New Haven, CT, USA

2011-2018 Ph.D., Yale University, New Haven, CT, USA

2009-2011 B.S., Stony Brook University, Stony Brook, NY, USA*

2007-2011 B.S., Nanjing University, Nanjing, Jiangsu, China*

* Degrees were conferred by both universities.

Research Interests

Antigen presentation is crucial for activating specific T cell immune responses and establishing immune surveillance, which serves as a bridge between innate and adaptive immunity. Just as the central dogma of "DNA → RNA → protein" laid the foundation for molecular genetics, the process of "antigen-presenting cells (APC) → T cells → target cells" forms the central dogma of immunology. However, tumor cells and pathogens have evolved various strategies to suppress antigen presentation and achieve immune evasion—this is also a key factor to cause resistance to immunotherapy. Therefore, exploring the regulatory mechanisms of antigen presentation in disease microenvironments will help us understand disease pathogenesis and promote the development of novel therapeutic strategies.

Our research group focuses on antigen presentation, particularly on antigen presentation mediated by major histocompatibility complex class I (MHC-I). By utilizing innovative screening platforms, combined with molecular and cellular biology, biochemistry, and various mouse models, we aim to deeply explore the regulatory mechanisms of classical antigen presentation and cross-presentation in tumor and other disease microenvironments, and use this as a foundation for developing innovative therapies.

The laboratory is recruiting assistant investigators, postdoctoral fellows, graduate students, laboratory technicians, and research assistants on a long-term basis. The group offers a cozy and collaborative scientific research environment, rich research resources and advanced experimental equipments, opportunities for learning and development, collaboration with senior researchers, and competitive salary and benefits. Applicants should send their CV and cover letter to qiao.lu@sjtu.edu.cn, and please indicate "Application for Lab Position - Name" in the subject line. We look forward to the participation of talented young individuals!